This nightstand from Two Way Mirrors has a pull out drawer under the top that can be used to conceal weapons or valuables, while keeping them close by.
Niangua Furniture makes this solid walnut and hickory dresser with a few surprises. There is a hidden drawer just underneath the top for storing valuables and private items. The sides of the cabinet also swing out to reveal large hidden storage...
A user on Gardenweb showcased these custom under cabinet storage drawers in their house. The hidden toe kick drawers have a latch that opens them when you push with your foot.